Microarray Evaluation of Dietary Restriction
نویسندگان
چکیده
منابع مشابه
Optimization of dietary restriction protocols in Drosophila.
Dietary restriction (DR) extends life span in many organisms, through unknown mechanisms that may or may not be evolutionarily conserved. Because different laboratories use different diets and techniques for implementing DR, the outcomes may not be strictly comparable. This complicates intra- and interspecific comparisons of the mechanisms of DR and is therefore central to the use of model orga...
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Caloric restriction is the most effective and reproducible dietary intervention known to regulate aging and increase the healthy lifespan in various model organisms, ranging from the unicellular yeast to worms, flies, rodents, and primates. However, caloric restriction, which in most cases entails a 20-40% reduction of food consumption relative to normal intake, is a severe intervention that re...
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I. White Carneau pigeons develop genetic atherosclerosis. The aorta shows intimal cushions at birth, cholesterol accumulation at 9 months of age and definite atherosclerotic lesions by 3 years of age. To determine whether these age-related arterial changes can be prevented by dietary restriction started early in life, ymonth-old pigeons were subjected to dietary restriction (40 % of ad lib. die...
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ژورنال
عنوان ژورنال: The Journal of Nutrition
سال: 2005
ISSN: 0022-3166,1541-6100
DOI: 10.1093/jn/135.6.1343